Table 5.
Subgroup analysis on the association between varus knee with incident osteoarthritis, adjusting for age, sex, and BMI.
| Subgroup | Number of cases | HR (95% CI) | P |
|---|---|---|---|
| Age | |||
| < 65 years (N = 812) | 7 (1.2%) | 1.78 (0.44, 6.78) | 0.42 |
| ≥ 65 years (N = 441) | 26 (4.9%) | 4.08 (1.68, 9.94) | 0.002 |
| Sex | |||
| Women (N = 884) | 28 (3.2%) | 3.17 (1.48, 6.82) | 0.003 |
| Men (N = 242) | 5 (2.1%) | 1.67 (0.27, 10.35) | 0.58 |
| BMI | |||
| Normal, < 23 kg/m2 (N = 579) | 10 (1.7%) | 1.66 (0.47, 5.88) | 0.44 |
| Overweight, < 23–24.9 kg/m2 (N = 247) | 6 (2.4%) | 2.78 (0.53, 14.53) | 0.23 |
| Obese, ≥ 25 kg/m2 (N = 300) | 17 (5.7%) | 5.25 (1.97, 14.02) | < 0.001 |
BMI, body mass index; CI, confidence interval; HR, hazard ratio.