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. 2024 Sep 18;27(10):110988. doi: 10.1016/j.isci.2024.110988

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This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

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Associations of ex-miRNA with platelet traits

(A and B) Volcano plots depicting ex-miRNA differential expression for (A) platelet count (PLT) and (B) mean platelet volume (MPV).

(C) Shows the associations of exQTLs, ex-miRNAs, and platelet traits, with beta and p values presented for miR-494-3p as a representative miRNA in 14q32. Given that ex-miRNA expression levels were assessed through Ct values (higher values indicating lower expression), positive associations correspond to negative beta estimates (red dots), and vice versa (blue dots). The term “non-significant” (green dots) refers to ex-miRNAs with an FDR >0.05. MR: Mendelian Randomization.