Table 2.

Comparison between intervention studies using Ayurvedic medicine in patients with Cerebral Palsy and spasticity.

Author	Design	Sample	Age	Inclusion Criteria	GRADE/MMAT	Place	Intervention	Control	Outcomes Found
Arun Raj, 2018 [27]	-Clinical trial -Unicentric -Open -Double arm, -Not randomized -Homogeneous population -Pilot study	32: 4 losses - final 28 (in 2 groups)	3–8 years	Spasticity in limbs with motor coordination failure, developmental delay, hyperreflexia.Ashworth scale	Moderate/moderate	College and Hospital of Ayurveda Hassan, India	-Group A: Abyanga with Tila Taila for 15 min. Dashamoola Kashaya, rest and application of Salavana Upanaha. (body manipulation and oral route)	-Group B (Salavana Upanaha): oral application only	-Group A: reduction of spasticity before and after use -Between groups: associated with body manipulation, greater reduction in spasticity -Group A: Mean spasticity scale from 3.45 (SD 0.69) at baseline to 1.27 (SD 0.38) -Group B: Mean spasticity scale from 3.54 (SD 0.70) at baseline to 2.06 (SD 1.06) -No adverse events
Palande, 2017 [30]	-Clinical trial -Unicentric -Open Randomized -Homogeneous population	30 (divided into 3 groups)	1–12 years	Children with cerebral palsy. Ashworth spasticity scale	Moderate/low	Balaroga Department, National Institute of Ayurveda, Jaipur, India	-Group A Shishukalyan Ghrita- 0.25 ml/kg/day in two to three divided doses + massage - 15–20 min a day. 90 days.	-Group B Kala Basti (therapeutic enema) - drugs 15 days + massage 15–20 min a day + medication group A. 90 Days -Group C Physiotherapy 30–35 min daily	-Group A: improvement 53.33% (p < 0.01) -Group B: 29.63% (p < 0.05) and group C 26.67% (p < 0.05) improvement before and after use -No significant difference in the intervention -Left upper limb with statistical difference in improvement in group A compared to C, no difference between group B and C. -Other members: no superiority between groups. -Ayurveda equally effective as physiotherapy, earlier -No adverse events