Serial No.. |
Study |
Title and year published |
Journal |
Sample size |
LAIs used |
Outcomes |
1. |
Sung Wan et al. [3] |
Use of long-acting injectable risperidone before and throughout pregnancy in schizophrenia (2007) |
Progress in Neuro-Psychopharmacology and Biological Psychiatry |
1 |
Risperidone LAI |
No adverse outcomes reported |
2. |
Orsolini et al. [4] |
Severe and persistent mental illness (SPMI) in pregnancy and breastfeeding: focus on second-generation long-acting injectable antipsychotics (2021) |
Expert Opinion on Drug Safety |
11 |
Five patients received aripiprazole; one patient received olanzapine; three patients received risperidone; two patients received paliperidone |
Three preterm vaginal deliveries |
3. |
Fernandez- Abascal et al. [5] |
Long-acting injectable aripiprazole in pregnant women with schizophrenia: a case-series report (2021) |
Therapeutic Advances in Psychopharmacology |
6 |
Aripiprazole; one woman interrupted LAI treatment at the end of the first trimester |
No adverse outcomes reported |
4. |
Nguyen et al. [6] |
Long-acting injectable antipsychotic treatment during pregnancy: outcomes for women at a tertiary maternity hospital (2022) |
Psychiatry Research |
36 |
One patient received haloperidol; two patients received fluphenazine; nine patients received flupenthixol; 12 patients received zuclopenthixol; eight patients received aripiprazole; two patients received paliperidone; four patients received risperidone |
Six preterm vaginal deliveries |
5. |
Eleftheriou et al. [1] |
Long-acting injectable antipsychotic treatment during pregnancy: a case series (2023) |
International Journal of Environmental Research and Public Health |
15 |
Five patients received paliperidone; 10 patients received aripiprazole |
two miscarriages; one still-birth; one preterm vaginal delivery |
6. |
Ballester-Garcia et al. [7] |
Use of long-acting injectable aripiprazole before and through pregnancy in bipolar disorder: a case report (2023) |
BMC Pharmacology and Toxicology |
1 |
Aripiprazole |
No adverse outcomes reported |