Rejection rates across resamples in applications of SiMMR to imaging and mobile health data. Each trace represents a different test statistic. Power curves for individual modalities are obtained through multivariate distance matrix regression (MDMR). PNC, Philadelphia Neurodevelopmental Cohort; FC, functional connectivity; rsFC, resting-state functional connectivity; SC, structural connectivity; EMA, ecological momentary assessment; MC-MDMR, multiple MDMR statistics after Bonferroni correction; MMR, multivariate multiple regression using Pillai’s trace.