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. 2024 Sep 30;50:102134. doi: 10.1016/j.tranon.2024.102134

Table 2.

BW cytology, BW sequencing, and histological classification by the characteristics of lung lesions in patients with early-stage lung cancer.

Location
Size
Bronchus sign
Necrosis
Inner Mid Outer P ≥3cm <3cm P Yes No P Yes No P
Positivity of BW cytology and BW sequencing, number of patients (%)
cpsp (n = 22) 8 (53.3) 10 (19.2) 4 (8.5) 0.014* 19 (33.9) 3 (5.2) 0.002* 21 (22.3) 1 (5.0) 0.196* 18 (40.9) 4 (5.7) <0.001*
cnsp (n = 20) 2 (13.3) 12 (23.1) 6 (12.8) 0.493* 13 (23.2) 7 (12.1) 0.230* 19 (20.2) 1 (5.0) 0.198* 15 (34.1) 5 (7.1) 0.003*
cpsn (n = 11) 3 (20.0) 5 (9.6) 3 (6.4) 0.391* 7 (12.5) 4 (6.9) 0.530* 10 (10.6) 1 (5.0) 0.689* 4 (9.1) 7 (10.0) >0.999*
cnsn (n = 61) 2 (13.3) 25 (48.1) 34 (72.3) 0.050* 17 (30.4) 44 (75.9) 0.010* 44 (46.8) 17 (85.0) 0.123* 7 (15.9) 54 (77.1) <0.001*
Sensitivity of BW cytology and BW sequencing, %
Cytology 73.3 28.8 14.9 <0.001 46.4 12.1 <0.001 33.0 10.0 0.056 50.0 15.7 <0.001
Seqencing 66.7 42.3 21.3 0.004 57.1 17.2 <0.001 42.6 10.0 0.005 75.0 12.9 <0.001
Cytology+Sequencing 86.7 51.9 27.7 <0.001 69.6 24.1 <0.001 53.2 15.0 0.002 84.1 22.9 <0.001
Histological classification, number of patients (%)
ADC 11 (73.3) 36 (69.2) 29 (61.7) 0.964# 32 (57.1) 44 (75.9) 0.125# 59 (62.8) 17 (85.0) 0.037# 24 (31.6) 52 (68.4) 0.038#
SQC 4 (26.7) 12 (23.1) 11 (23.4) 16 (28.6) 11 (19.0) 26 (27.6) 1 (5.0) 15 (55.6) 12 (44.4)
SCLC 0 (0.0) 4 (7.7) 7 (14.9) 8 (14.3) 3 (5.2) 9 (9.6) 2 (10.0) 5 (45.5) 6 (54.5)

BW = bronchial washing; cpsp = cytology positive / sequencing positive; cnsp = cytology negative / sequencing positive; cpsn = cytology positive / sequencing negative; cnsn = cytology negative / sequencing negative; ADC = adenocarcinoma; SQC = squamous cell carcinoma; SCLC = small cell carcinoma.

The numbers in parentheses represent the percentage of patients relative to the total number of patients in that column.

vs. total.

#

ADC vs. SQC.