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. Author manuscript; available in PMC: 2024 Oct 14.
Published in final edited form as: Nat Chem Biol. 2022 Sep 22;18(11):1277–1286. doi: 10.1038/s41589-022-01138-9

Extended Data Fig. 8. Maximum likelihood phylogeny of emtA homologs.

Extended Data Fig. 8.

Branch lengths are proportional to the number of substitutions. The tree is annotated with circles showing the presence (red) or absence (blue) of the emtAL uORF in 5’UTR of the emtA genes, where the 5’UTR is confidently alignable. The sequences of the encoded leader peptides are indicated. The asterisk indicates peptides from two annotated neighboring ORFs in Paenactinomyces guangxiensis, corresponding to the N and C terminal regions of EmtA. The interruption of the emtA ORF suggests pseudogenation caused by a frameshift.