Table 1.
Characteristic of luminal B breast cancer patients with and without malignant pleural effusions
| Variables | With MPE (n = 54) | Without MPE (n = 87) | P |
|---|---|---|---|
| Age at surgery (years) | 0.096 | ||
| < 50 | 32 (59.3%) | 39(44.8%) | |
| ≥ 50 | 22(40.7%) | 48 (55.2%) | |
| Primary tumor location | |||
| Left | 25 (46.3%) | 50 (57.5%) | 0.186 |
| Right | 26 (48.1%) | 36 (41.4%) | |
| Bilateral | 3 (5.6%) | 1 (1.1%) | |
| Clinical stages at initial diagnosis | |||
| Stage I | 5 (9.3%) | 11 (12.6%) | 0.088 |
| Stage II | 15 (27.8%) | 26 (29.9%) | |
| Stage III | 22 (44.4%) | 36 (41.4%) | |
| Unknown | 10 (18.5%) | 4 (4.6%) | |
| Histological type | |||
| Invasive ductal carcinoma | 50 (92.6%) | 83 (95.4%) | 0.787 |
| Invasive lobular carcinoma | 1(1.9%) | 1(1.1%) | |
| Others | 3 (5.6%) | 3 (3.4%) | |
| HER-2 | |||
| Positive | 8 (14.9%) | 12 (13.8%) | 0.866 |
| Negative | 46 (85.2%) | 75 (86.2%) | |
| Metastatic site | 0.502 | ||
| Lung | 22(40.7%) | 29(33.3%) | |
| Liver | 12(22.2%) | 24(27.6%) | |
| Bone | 27(50.0%) | 28(32.2%) | |
| Others | 42(77.8%) | 50(57.5%) | |
| Neoadjuvant therapy | |||
| Yes | 11 (20.3%) | 13 (14.9%) | 0.404 |
| No | 43 (79.6%) | 74 (85.0%) | |
| Adjuvant Therapy | |||
| Chemotherapy | 45 (83.3%) | 68 (78.2%) | 0.316 |
| Endocrine therapy | 34 (63.0%) | 51 (58.6%) | |
| Radiotherapy | 24 (44.4%) | 22 (25.3%) | |
| Surgical approach | |||
| Radical surgery | 49 (83.3%) | 84 (96.6%) | 0.260 |
| Conservative surgery | 5 (9.3%) | 3 (3.4%) |
MPE, Malignant pleural effusion