Fig. 2.

Panel A: ROC curves reveal better discrimination of circulating angiotensinogen (Aogen; AUC = 0.82 [0.70, 0.93]) for mortality than serum lactate (AUC = 0.68 [0.57, 0.80]) or active renin (AUC = 0.73 [0.61, 0.86]) in the VICTAS cohort of sepsis patients at baseline (day 0, N = 103). Panels B–D: Kaplan–Meier estimates of survival curves reveal a stronger association of serum levels of Aogen (log rank p = 0.003) with mortality than renin (log rank p = 0.024) or lactate (log rank p = 0.603) in the VICTAS cohort at baseline (day 0)