Table 1.
Clinical characteristics of patients and controls.
| Patients | Healthy controls | |
|---|---|---|
| n=23 | n=10 | |
| Demographic characteristics | ||
| Age, years (median, IQR) | 74 (69-85) | 76 (69-83) |
| Male (n, %) | 13 (57) | 6 (60) |
| Infection type | ||
| Urinary tract (n, %) | 17 (74) | – |
| Pulmonary (n, %) | 2 (8.7) | – |
| Intestinal (n, %) | 4 (17.3) | – |
| Bacterial species | ||
| Escherichia coli (n, %) | 17 (74) | – |
| Pseudomonas aeruginosa (n, %) | 2 (8.7) | – |
| Klebsiella oxytoca (n, %) | 1 (4.3) | – |
| Klebsiella pneumonia (n, %) | 1 (4.3) | – |
| Serratia marcescens (n, %) | 1 (4.3) | – |
| Proteus mirabilis (n, %) | 1 (4.3) | – |
| Severity* | ||
| Infection | 21 (91.3) | – |
| Sepsis | 2 (8.7) | – |
| Septic shock | 0 (0) | – |
| Neutrophil-to-lymphocyte ratio (median, interquartile range) | 6.6 (3.3-29.1) | 1.4 (1.2-5.0) |
| C-reactive protein** (median, IQR) | 144.8 (118.4-271.8) | – |
| Pro-calcitonin*** (median, IQR) | 0.6 (0.28-37.0) | – |
| Outcome (day 30 mortality) (n, %) | 1 (4.3) | 0 (0) |
*Sepsis-3 definition with qSOFA score after Singer et al., JAMA 2016.
**CRP is measured in mg/L. Normal values are below 10 mg/L.
***Pro-calcitonin is measured in ng/ml. Normal values are below 0.25 ng/ml.
IQR, interquartile range.