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. Author manuscript; available in PMC: 2024 Oct 14.
Published in final edited form as: Compr Physiol. 2023 Mar 30;13(2):4409–4491. doi: 10.1002/cphy.c190043

Figure 4. Steroid-binding properties of the human mineralocorticoid receptor (MR) expressed in cultured cells.

Figure 4.

(A) Scatchard analysis of tritiated aldosterone binding in extracts prepared from pRShMR-transfected COS cells (B and C) Competition of unlabeled steroids for binding with 5 nM [3H] aldosterone in transfected COS cell extracts Abbreviations: Aldo, aldosterone, Doc, deoxycorticosterone; Dex, dexamethasone; Spiro, spironolactone; E2, 17β-estradiol; CS, corticosterone; HC, hydrocortisone; and Prog, progesterone. Figure adapted from Arriza et al (28).