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. Author manuscript; available in PMC: 2024 Oct 14.
Published in final edited form as: Compr Physiol. 2023 Mar 30;13(2):4409–4491. doi: 10.1002/cphy.c190043

Table 1 -.

Normal Circulating Levels of Hormones and Associated Pathologies

Hormone Ranges References
Aldosterone
  • ~4–31 ng/dL (~110–860 pmol/L) – Adults, upright position

  • ~3–16 ng/dL (~83–444 pmol/L) – Adults, supine position

(198, 213, 305)
Renin
  • 0.6 – 4.3 ng/mL/hr – Age 18 –39

  • 0.6 – 3.0 ng/mL/hr – Age 40+

(416, 592)
Cortisol
  • 6–25 mcg/dL (A.M. reading)

  • 2–14 mcg/dL (P.M. reading)

(66, 415)
Aldosterone Level Renin Level Cortisol Level Pathology References
High Low Normal Conn’s syndrome/primary hyperaldosteronism (131, 214)
High High Normal Secondary hyperaldosteronism (131, 214)
Low High Low Addison’s disease/primary adrenal insufficiency (131, 214)