TABLE 1.
Passive protection by adoptive transfer of antibodies but not splenocytes
Transferred materiala | % Survivors (no. of survivors/no. total)
|
|||
---|---|---|---|---|
Serac | Splenocytesc | T-cell-enriched splenocytes | B cells | |
Live virus | 100 (7/7) | 27 (3/11) | 0 (0/4) | 0 (0/4) |
pE (i.m.e) | 75 (6/8) | 0 (0/6) | 0 (0/5) | 0 (0/5) |
pE (gene gun) | 67 (6/9) | 0 (0/6) | 0 (0/5) | 0 (0/4) |
pcDNA3b | 0 (0/7) | 0 (0/6) | NDd | ND |
Naïve | 0 (0/5) | 0 (0/9) | ND | ND |
Transferred materials were prepared from C3H/HeN mice that were immunized with DNA or live JEV vaccines as described in the legend to Fig. 4.
Data are included for both intramuscular and gene gun immunization.
Data are from two independent experiments.
ND, not done.
i.m., intramuscular.