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. 2024 Oct 1;16:1462238. doi: 10.3389/fnagi.2024.1462238

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Copyright © 2024 Xue, Lei, Liu, Guo, Yan, Jin and Yu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Olfactory dysfunction in C. elegans models of neurodegenerative diseases. (A, B) Chemotaxis responses of wild-type adults and adults with pan-neuronal expression of Aβ1-42 to various odors on the first (A) and sixth (B) days of adulthood. (C, D) Chemotaxis responses of wild-type adults and adults with pan-neuronal expression of Q40 to various odors on the first (C) and sixth (D) days of adulthood. Data are from three or more independent experiments, and are presented as mean ± s.e.m. P values are derived from two-way ANOVA with Sidak's multiple comparisons test. ^*P < 0.05; ^**P < 0.01; ^***P < 0.001; ^****P < 0.0001; n.s., not significant. 2-BU is 2-butanone, and 2-NO is 2-nonanone.