TABLE 1.
The highly-recurrent germline hereditary fusion genes (HFGs) associated with DCM.
| HFGs | DCM (122) | GTEx (252) | Folds | ||
|---|---|---|---|---|---|
| # | % | # | % | ||
| RYR2-ACTN2 | 107 | 87.70 | 54 | 21.43 | 4.1 |
| NDUFV1-ACTG1 | 89 | 72.95 | 45 | 17.86 | 4.1 |
| TINAGL1-ACTG1 | 62 | 50.82 | 56 | 22.22 | 2.3 |
| TTN-LSM1 | 49 | 40.16 | 19 | 7.54 | 5.3 |
| C20orf166-C9orf3 | 48 | 39.34 | 23 | 9.13 | 4.3 |
| C20orf166-MYH6 | 45 | 36.89 | 42 | 16.67 | 2.2 |
| PCBP3-USP28 | 39 | 31.97 | 12 | 4.76 | 6.7 |
| MYH7-C9orf3 | 31 | 25.41 | 10 | 3.97 | 6.4 |
| TPM2-ACTG1 | 30 | 24.59 | 30 | 11.90 | 2.1 |
| TTN-LMF1 | 29 | 23.77 | 7 | 2.78 | 8.6 |
| RYR2-ACTN2 | 27 | 22.13 | 3 | 1.19 | 18.6 |
| TTN-PPFIA1 | 25 | 20.49 | 13 | 5.16 | 4.0 |