Table 1.
Demographics and clinical characteristics of LN patients in cross-sectional study.
| Renal flare | Remission | P value | |
|---|---|---|---|
| Age (year) | 37.74 ± 10.74 | 39.80 ± 10.37 | <0.0001 |
| Gender (F: M) | 29: 12 | 27: 12 | >0.999 |
| a Duration of SLE (y) | 5.08 (0.25, 15.57) | 7.44 (3.29,17.94) | 0.136 |
| a Duration of LN (y) | 4.81 (0.04, 13.32) | 7.01 (2.87, 14.37) | 0.079 |
| SLEDAI-2K score | 11.74 ± 2.87 | 2.72 ± 2.72 | <0.0001 |
| Renal SLEDAI-2K score | 5.37 ± 3.18 | 0.61 ± 1.46 | <0.0001 |
| Serum anti-dsDNA antibody (IU/ml) | 133.10 ± 100.30 | 80.44 ± 86.48 | 0.023 |
| Serum C3 (mg/dl) | 47.74 ± 18.10 | 80.33 ± 25.64 | <0.0001 |
| eGFR (ml/min/1.73m2) | 68.84 ± 29.81 | 81.78 ± 29.14 | 0.036 |
| Serum creatinine (µmol/l) | 113.70 ± 64.66 | 106.70 ± 138.40 | 0.047 |
| Serum urea (mmol/l) | 12.12 ± 9.38 | 7.64 ± 5.76 | 0.002 |
| Serum albumin (g/l) | 29.29 ± 6.79 | 41.22 ± 3.19 | <0.0001 |
| Urine albumin-to-creatinine ratio (mg/mmol Cr) | 470.00 ± 332.60 | 54.78 ± 35.20 | <0.0001 |
| Serum IgG (mg/dl) | 1287.00 ± 811.30 | 1278.00 ± 464.20 | 0.569 |
| Serum IgA (mg/dl) | 270.00 ± 136.70 | 226.00 ± 91.92 | 0.375 |
| Serum IgM (mg/dl) | 89.77 ± 58.54 | 78.24 ± 46.20 | 0.599 |
| Prednisolone dose (mg/day) | 32.53 ± 12.85 | 6.81 ± 1.17 | <0.0001 |
| Renal biopsy activity score | 7.14 ± 3.38 | ||
| Renal biopsy chronicity score | 2.02 ± 2.03 | ||
| Correlation of serum CD44 level with activity score | 0.37 | 0.025 | |
| Correlation of serum CD44 level with leukocyte infiltration | 0.45 | 0.018 | |
| Correlation of serum CD44 level with interstitial inflammation | 0.37 | 0.049 |
Results expressed as mean ± SD.
a
Duration of SLE and LN expressed as median (25 and 75% percentile).