Table 5.

Predictors of cholangitis.

Variables	Univariate analysis			Multivariate analysis
	Hazard ratio	95% CI	P value	Hazard ratio	95% CI	P value
Age	1.048	0.990-1.109	0.104
Gender
Male	1
Female	0.753	0.300-1.888	0.545
Tumor stage
III	1
IV	2.212	0.859-5.697	0.100
ECOG PS	0.664	0.396-1.114	0.121
Bismuth type
II	1
III	1.091	0.415-2.868	0.860
IV	0.477	0.095-2.395	0.369
TBIL	1.000	0.996-1.004	0.994
Ca19-9	1.000	0.999-1.000	0.236
Stent insertion
Unilateral	1
Bilateral	1.387	0.553-3.477	0.486
Post-operative chemotherapy
No	1
Yes	0.772	0.298-2.001	0.594

ECOG PS, Eastern Cooperative Oncology Group performance status; TBIL, total bilirubin.