FIG. 5.

Pathogenicity of recombinant RVs. Two-days-old suckling mice were inoculated with recombinant RVs at a dose of 100 or 100,000 FFU/mouse i.m. Results recorded at the end of the observation period of 10 or 21 days are presented. All animals inoculated with SAD-L16 (L16), L-ΔP7 (L7), L-ΔP11 (L11), and SAD-D29 (D29) died of rabies within 10 days after inoculation. At the end of 21 days of observation, the number of mice that died of rabies in the groups inoculated with 100 FFU/mouse of D-ΔP7 (D7) or D-ΔP11 (D11) was one and zero, respectively.