Fig. 3. Multi-site characterization of human breast tissue.
Representative REIMS spectra from either normal breast adipose a or invasive breast cancer b. The spectra shown are 1 s scans acquired using cut mode, and subjected to background subtraction and lockmass correction. The PCA c and PCA/LDA d plots compare the overall tissue-type variability between cut and coagulation modes. e–g Differential abundance of selected ions identified by peak picking, used to create a model with only 11 targeted ions.