Fig. 2.

Effects of low to moderate ethanol exposure from IKK-α/β to IκB-α on LRP1 expression and NF-κB signaling in presymptomatic APP/PS1 mice. (A and B) Western blot quantification of LRP1/IKK-α/β/IκB α/NF-κB signaling. (C and D) Western blot results of LRP1/IKK-α/β/IκB-α/NF-κB in the cortex and hippocampus of the presymptomatic APP/PS1 mice brains. β-Actin was used as a loading control. (A and C) Cortex, (B and D) Hippocampus. Data represent mean ± SEM; n = 5 per group. *P < 0.05 comparing each group. Two-tailed Mann–Whitney test. See Fig. S17 for a full Western blot and see Table S1 for full statistical information.