Fig. 5.

[¹⁸F] Fluorodeoxyglucose uptake measured by in vivo microPET. (A) Representative FDG-PET images from air-exposed and ethanol-exposed presymptomatic APP/PS1 mice. The boundaries of ROIs were drawn on the coronal section. Glucose uptake increased in the cortex and hippocampus of ethanol exposed presymptomatic APP/PS1 mice. Quantification of glucose uptake by FDG-PET imaging in the cortex (B) and hippocampus (C). Data represent mean ± SEM; n = 10 per group. *P < 0.05 comparing each group. Two-tailed Mann–Whitney test. See Table S1 for full statistical information.