Table 1.

Tumor incidence, latency, and growth rate in AAV mouse models

AAV model	KSP-Cre AAV-> LSL-Cas9/+	Creless AAV-> LSL-Cas9/+; Pax8 Cre
No. of mice with tumor (% penetrance)	8/24 (33%)	19/23 (83%)
Time to initial tumor detection by MRI (range)	14 wk (14 to 32 wk)	9 wk (9 to 20 wk)
Mean tumor growth rate	0.78 mm/week	0.96 mm/week