Figure 3.

Patients receiving maintenance PARPi had more favorable rwPFS and tended to have more favorable rwOS when HRDsig(+) but not HRDsig(−). rwPFS is shown by maintenance therapy received for (A) HRDsig(+) and (B) HRDsig(−). rwOS is shown by maintenance therapy received for (C) HRDsig(+) and (D) HRDsig(−). rwOS estimates are risk set adjusted to account for delayed entry to at-risk table (see “Materials and Methods”). Kaplan–Meier curves are adjusted by propensity weights (see Supplementary Fig. S1). Analyses unadjusted for propensity weights have similar results (see Supplementary Fig. S5). tx, therapy.