Table 1. Key characteristics of FLiP very preterm born children and adolescents, their control siblings, and age, sex and nationality matched control participants from Ciao Corona.
Characteristic | FLiP pretermN=442 | FLiP controlN=145 | Ciao Corona controlN=882 |
Age (years) | 10 (5–16) | 9 (5–19) | 10 (6–16) |
Sex (male) | 236 (53%) | 84 (59%) | 472 (54%) |
Gestational age (weeks) | |||
24–27 | 130 (29%) | ||
28–31 | 312 (71%) | ||
Birth weight | |||
<1000 g | 158 (36%) | ||
1000+ g | 284 (64%) | ||
Multiple gestation | 140 (32%) | ||
Socioeconomic status | 5 (3, 6) | 5 (3, 6) | 4 (3, 5) |
Non-Swiss nationality | 66 (15%) | 20 (14%) | 121 (14%) |
Moderate to severe BPD | 55 (12%) | ||
Coughing/wheezing restrict daily activities | 13 (2.9%) | 1 (0.7%) | |
Any chronic health condition | 104 (24%) | 12 (8.3%) | 122 (14%) |
Chronic non-respiratory conditions | 67 (15%) | 11 (7.6%) | 96 (11%) |
Chronic respiratory conditions | 24 (5.4%) | 3 (2.1%) | 34 (3.9%) |
Cerebral palsy | 33 (7.5%) | 1 (0.7%) | 0 (0%) |
Physical activity (hours per day) | 0.71 (0.50, 1.00) | 0.71 (0.57, 1.14) |
BPD indicates bronchopulmonary dysplasia. Chronic health conditions included asthma, cystic fibrosis, congenital heart defects, heart disease, celiaccoeliac, diabetes, inflammatory bowel disease, high blood pressure, attention deficit hyperactivity disorder, epilepsy, joint disorders, depression/anxiety, and cerebral palsy. Socio-economic status is measured on the basis of parents’ education from 2 (both parents havinghave university education) to 12 (both parents have less than compulsory education) points, though the categories differed somewhat in FLiP and Ciao Corona. As physical activity was assessed using different questions in Ciao Corona than in FLiP that were not comparable, we did not include physical activity in Ciao Corona here.
BPDbronchopulmonary dysplasiaFLiPFrühgeborenen Lungen Projekt/Premature Infant Lung Project