Table 2.
Genetic clusters associated with secondary metabolite production on the Bacillus LB7 strain genome.
| Region | Type | Nucleotide | Most similar known cluster | Similarity | Associated function | |
|---|---|---|---|---|---|---|
| From | To | |||||
| 1 | RiPP-like | 4,945 | 14,996 | – | – | – |
| 2 | NRPS | 110,191 | 191,630 | Bacitracin | 100% | Antibiotic |
| 3 | T3PKS | 321,196 | 362,293 | – | – | – |
| 4 | NRPS, T1PKS, terpene | 379,128 | 456,657 | – | – | – |
| 5 | NRPS | 1,782,655 | 1,836,429 | Lichenysin | 100% | Antibiotic, Surfactant |
| 6 | NRPS, betalactone | 2,283,464 | 2,333,014 | Fengycin | 86% | Antibiotic, antifungal |
| 7 | Siderophore | 2,467,109 | 2,482,499 | – | – | – |
| 8 | CDPS | 2,831,750 | 2,852,499 | – | – | – |
| 9 | NRPS | 3,334,166 | 3,381,323 | Bacillibactin | 53% | Antibiotic, antitumor, siderophores |
| 10 | Lassopeptide | 3,488,454 | 3,510,927 | – | – | – |
| 11 | Thiopeptide, RiPP-like | 3,734,656 | 3,775,831 | Butirosin A/Butirosin B | 7% | Aminoglycoside antibiotic |
Clusters unmatched with known clusters are denoted with “-.”