Pre- and post-target site registration clinical, and related OCT most representative scans, compared to histopathology confirmatory images of three selected cases of OL, OLP and OSCC (a,b): pre-site registration clinical image (a) and OCT scan (b) of a case of homogeneous OL on the left buccal mucosa. (c,d): pre-site registration clinical image (c) and OCT scan (d) of a case of reticular OLP on the dorsal surface of the tongue. (e,f): pre-site registration clinical image (e) and OCT scan (f) of a case of OSCC on lower anterior alveolar mucosa. (g,h): post-site registration clinical image (c) and OCT scan (d) of the previous OL case. (i,j): post-site registration clinical image (i) and OCT scan (j) of the previous OLP case. (k,l): post-site registration clinical image (k) and OCT scan (l) of the previous OSCC case. (m–o): histopathology confirmatory images (H&E stain; original magnification ×2.5) of the previous OL, OLP and OSCC cases, ((m), (n), (o) respectively). KL: Keratinized Layer; SEL: Stratified Epithelial Layer; BM: Basement Membrane; LP: Lamina Propria; white arrows (↑): ‘icicle-like’ structures.