Table 1.
Diagnostic accuracy measures for OCT compared to histopathology findings. Pre-target indicates the OCT evaluation pre-target site registration; post-target indicates the OCT evaluation post-target site registration.
| Predictive Value % (95% CI) |
||||
|---|---|---|---|---|
| Observer 1 | Sensitivity % (95% CI) |
Specificity % (95% CI) |
Positive | Negative |
| Pre-target | ||||
| OSCC | 82.86, (71.97–90.82) |
97.86, (93.87–99.56) |
95.08, (86.26–98.35) |
91.95, (87.21–95.03) |
| OL | 70.00, (57.87–80.38) |
85.00, (77.99–90.47) |
70.00, (60.45–78.08) |
85.00, (79.74–89.08) |
| OLP | 68.57, (56.37–79.15) |
77.86, (70.07–84.43) |
60.76, (52.21–68.70) |
83.21, (77.61–87.63) |
| Post-target | ||||
| OSCC | 98.57, (92.30–99.96) |
100.00, (97.40–100.00) |
100.00, (94.79–100.00) |
99.29, (95.24–99.90) |
| OL | 98.57, (92.30–99.96) |
98.57, (94.93–99.83) |
97.18, (89.70–99.27) |
99.28, (95.17–99.90) |
| OLP | 97.14, (90.06–99.65) |
98.57, (94.93–99.83) |
97.14, (89.56–99.26) |
98.57, (94.62–99.63) |
| Observer 2 | ||||
| Pre-target | ||||
| OSCC | 82.86, (71.97–90.82) |
98.57, (94.93–99.83) |
96.67, (87.94–99.14) |
92.00, (87.29–95.06) |
| OL | 70.00, (57.87–80.38) |
84.29, (77.18–89.88) |
69.01, (59.57–77.10) |
84.89, (79.60–89.00) |
| OLP | 68.57, (56.37–79.15) |
78.57, (70.84–85.05) |
61.54, (52.88–69.52) |
83.33, (77.78–87.72) |
| Post-target | ||||
| OSCC | 98.57, (92.30–99.96) |
100.00, (97.40–100.00) |
100.00, (94.79–100.00) |
99.29, (95.24–99.90) |
| OL | 98.57, (92.30–99.96) |
98.57, (94.93–99.83) |
97.18, (89.70–99.27) |
99.28, (95.17–99.90) |
| OLP | 97.14, (90.06–99.65) |
98.57, (94.93–99.83) |
97.14, (89.56–99.26) |
98.57, (94.62–99.63) |