Table 1.
Baseline characteristics of the study cohort.
| Variables | Overall (n = 182) | MR-PDFF < 6% (n = 77) | MR-PDFF ≥ 6% (n = 105) | p |
|---|---|---|---|---|
| Age, y | 51.16 ± 15 | 47.2 ± 15.7 | 54.1 ± 13 | 0.002 |
| Female, n (%) | 94 (51.6) | 51 (66.2) | 43 (41) | 0.001 |
| BMI, kg/m2 | 29.8 ± 4.9 | 28.3 ± 4 | 30.9 ± 5.3 | <0.001 |
| Waist circumference | 102.9 ± 12.4 | 97.2 ± 11.9 | 107.1 ± 11 | <0.001 |
| Diabetes, n (%) | 30 (16.7) | 6 (8) | 24 (22.9) | 0.009 |
| AST, IU/L | 21 (13) | 18 (7) | 24 (16) | <0.001 |
| ALT, IU/L | 25 (20) | 24 (16) | 32 (29) | <0.001 |
| Glycemia, mg/dL | 97 ± 18.6 | 89.6 (10.4) | 103.2 (21.5) | <0.001 |
| Triglycerides, mg/dL | 103 (69) | 87.5 (39) | 123 (97) | <0.001 |
| Cholesterol, mg/dL | 192.6 ± 46.3 | 195.7 ± 46.9 | 190.1 ± 45.9 | 0.48 |
| Platelet, 109/L | 244 ± 65.4 | 251 ± 66.6 | 239.2 ± 65.1 | 0.27 |
| GGT, IU/L | 27 (27) | 16 (14) | 36 (33) | <0.001 |
| MRI-PDFF, % | 7.2 (9.9) | 3.7 (2.3) | 13 (9.8) | <0.001 |
| AC-5M, dB/cm/MHz | 0.68 ± 0.13 | 0.57 ± 0.06 | 0.76 ± 0.10 | <0.001 |
| AC-5A, dB/cm/MHz | 0.68 ± 0.13 | 0.57 ± 0.06 | 0.76 ± 0.10 | <0.001 |
| AC-3A, dB/cm/MHz | 0.68 ± 0.13 | 0.57 ± 0.06 | 0.76 ± 0.11 | <0.001 |
Numbers in parentheses represent interquartile range unless otherwise specified. Abbreviations: AC-5M, attenuation coefficient (median of five measurements); AC-5A, attenuation coefficient (average of five measurements); AC-3A, attenuation coefficient (average of three measurements); AST, aspartate transaminase; ALT, alanine transaminase; BMI, body mass index; GGT, gamma-glutamyl transferase; MRI-PDFF, magnetic resonance imaging proton density fat fraction; p, probability of α type I error.