. 2022 Oct 25;30(10):1145–1174. doi: 10.2174/0929867329666220829091830

Table 2. Molecular structures (8a-i) and in vitro results for different breast cancer cell lines (Growth inhibitory concentration (GI₅₀, µM)).

Compounds 8a-i	MDA MB-231 ATTC	MCF-7	T-47D	NCI ADR-RES	HS-578T	MDA MB-435	MiDA-N	BT 549
8a	61.2	85.8	NT**	NT**	NT**	NT**	1.34	9.13
8b	IA*	99.8	45.6	IA*	61.8	42.8	34.8	37.7
8c	4.90	IA*	63.4	IA*	8.04	9.30	2.86	IA*
8d	6.21	IA*	2.45	2.76	IA*	2.75	IA*	IA*
8e	23.8	19.8	54.8	98.0	IA*	39.9	23.8	11.8
8f	7.36	4.72	62.5	7.4	6.72	8.62	7.00	4.12
8g	28.0	40.8	22.2	IA*	61.8	61.0	56.8	11.8
8h	IA*	IA*	IA*	IA*	IA*	IA*	IA*	IA*
8i	IA*	79.8	26.5	28.0	IA*	IA*	26.5	11.8

*IA: Inactive; GI₅₀ >100 µM, **NT: not tested.

Table 2. Molecular structures (8a-i) and in vitro results for different breast cancer cell lines (Growth inhibitory concentration (GI50, µM)).