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FIG. 2.

FIG. 2

Protection of guinea pigs with LGP-VRP and LNP-VRP against lethal challenge with Lassa virus. Viremia (A) and survival (B) are shown. Guinea pigs were immunized s.c. with LGP-VRP (LGP), LNP-VRP (LNP), a mixture of both LGP-VRP and LNP-VRP (LGP+LNP), or control ENP-VRP expressing ENP. The animals were challenged s.c. with 160 LD50 of Lassa virus. Error bars, standard deviations.