Table 1.
Clinical and demographic characteristics of the discovery (Bordeaux) and validation (Dijon) case‐control samples
| Bordeaux sample set | Dijon sample set | |||
|---|---|---|---|---|
| Cases (N = 209) | Controls (N = 209) | Cases (N = 212) | Controls (N = 212) | |
| Age (years) | 75.9 ± 4.5 | 75.7 ± 4.2 | 76.5 ± 5.2 | 76.1 ± 4.7 |
| Gender (male/female) | 71/138 | 71/138 | 78/134 | 78/134 |
| Education level, ≥ secondary school (%) | 28.7 | 28.7 | 28.3 | 28.3 |
| BMI (kg m–2) | 26.8 ± 4.4 | 26.1 ± 3.6 | 25.8 ± 4.6 | 25.1 ± 3.6 |
| Mini‐Mental State Examination | 26.9 ± 2.2 | 28.0 ± 1.6 | 25.9 ± 2.4 | 28.7 ± 1.0 |
| Benton Visual Retention Test | 10.8 ± 2.1 | 11.7 ± 1.9 | 10.0 ± 2.3 | 12.6 ± 1.6 |
| Isaac's Set Test | 27.7 ± 5.9 | 31.0 ± 6.1 | 28.0 ± 6.6 | 38.0 ± 6.2 |
| Trail‐Making Test part A | 24.2 ± 7.9 | 29.4 ± 9.1 | 22.2 ± 9.6 | 35.6 ± 11.1 |
| Trail‐Making Test part B | 10.0 ± 5.8 | 14.5 ± 6.5 | 7.8 ± 5.0 | 19.0 ± 6.7 |
| Number of medications regularly consumed | 4.9 ± 2.7 | 4.1 ± 2.4 | 5.5 ± 3.0 | 4.0 ± 3.0 |
| ApoE‐ε4 (%) | 25.8 | 12.0 | 26.9 | 20.8 |
| Diabetes (%) | 12.9 | 5.7 | 12.7 | 5.7 |
| History of cardiovascular diseases (%) | 33.5 | 27.8 | 41.0 | 30.2 |