Table 2.
Characteristics of All Pseudomonas aeruginosa Posttraumatic Osteomyelitis Episodes Followed up, April 2018 to January 2022, Médecins Sans Frontières–Supported Facilities in Mosul (Iraq) and Gaza (Palestine)
Characteristic per PAPTO Episode | Total Episodes (n = 66) |
Mosul (n = 21) |
Gaza (n = 45) |
P Valuea |
---|---|---|---|---|
Hospitalization and clinical characteristics | ||||
Length of stay, d, median (IQR) | 42 (24–53) | 30 (21–48) | 43 (24–60) | .30 |
Surgical interventions, median (IQR) | 2 (1–5) | 4 (1–6) | 1 (1–5) | .05 |
Clinical signs of infection at admission | ||||
Yes | 62 (93.9) | 21 (100.0) | 41 (91.1) | .30 |
No | 4 (6.1) | 0 (0.0) | 4 (8.9) | |
Months of follow-up during study period | ||||
≤6 mo | 28 (46.7) | 13 (68.4) | 15 (36.6) | .02 |
>6 mo | 32 (53.3) | 6 (31.6) | 26 (63.4) | |
Days completed under follow-up, median (IQR) | 203 (72–443) | 86 (24–213) | 294 (111–475) | .01 |
Time from injury to first biopsy, d, median (IQR) | 357 (37–698) | 394 (20–1153) | 324 (45–635) | .27 |
Biopsy-related characteristics | ||||
Bone samples collected per episode, median (IQR) | 5 (4–5) | 4 (3–5) | 5 (4–5) | .01 |
Time from sample collection to biopsy results, d, median (IQR) | 5 (4–7) | 4 (3–4) | 6 (4–8) | <.001 |
Length of treatment, d, mean (SD) | 45.5 (15.6) | 39.4 (9.6) | 48.4 (17.1) | .032 |
Infection-related characteristics | ||||
Polymicrobial | ||||
Yes | 49 (74.2) | 12 (57.1) | 37 (82.2) | .03 |
No | 17 (25.8) | 9 (42.9) | 8 (17.8) | |
Multidrug-resistant PTOb | ||||
Yes | 43 (65.1) | 12 (57.1) | 31 (68.9) | .35 |
No | 23 (34.8) | 9 (42.9) | 14 (31.1) | |
Multidrug-resistant PAPTO | ||||
Yes | 25 (37.9) | 4 (19.0) | 21 (46.7) | .06 |
No | 41 (62.1) | 17 (81.0) | 24 (53.3) |
Data are presented as No. (%) unless otherwise indicated.
Abbreviations: IQR, interquartile range; PAPTO, posttraumatic osteomyelitis caused by Pseudomonas aeruginosa; PTO, posttraumatic osteomyelitis; SD, standard deviation.
a P < .05 is statistically significant.
bCalculated among recurrent infections including non-PAPTO (new infections isolated from PAPTO patients, caused by bacteria other than P aeruginosa).