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Calculated Energetics of the Four State Model
| Ligand Condition | Ionic Strength (mM KCl) | (kcal/mol) | (kcal/mol) |
|---|---|---|---|
| Apo | 150 | 1.14 ± 0.03 | -- |
| 500 | 1.2 ± 0.03 | -- | |
| cAMP | 150 | -- | -- |
| 500 | < −2.7 ± 0 | < −3.9 ± 0.03 | |
| cGMP | 150 | 0.67 ± 0.03 | −0.47 ± 0.04 |
| 500 | 0.38 ± 0.02 | −0.82 ± 0.04 |
Energies are reported in mean values ± SEM.
