Fig. 2.

QC alleviated the swelling of the mLNs s in lupus-like mice. After 15 weeks of treatment, (A) Spleen size and statistical analysis of spleen of weight and cell counts from MRL/lpr mice in QC group and control group. (B) The weight and lymphocyte cell counts of mLNs from MRL/lpr mice in the QC group and control group were statistically analysed. (C, D) Representative flow diagrams of the frequency of Tfh cells and senescent CD4⁺ T cells from the spleen and mLNs of MRL/lpr mice with QC or vehicle. (E, F) Statistical analysis of cell counts of Tfh (CD4⁺PD⁻1⁺CXCR5⁺) and senescent CD4⁺ T cells (CD4⁺CD44^hiCD62L⁻PD-1⁺CD153⁺) from the mLNs and spleen of MRL/lpr mice. (Quercetin: n = 5, Control: n = 5, *P < 0.05)