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In vivo basal cardiac parameters of diastolic function. (a) EDP, end diastolic pressure; (b) dP/dtmin, rate of relaxation; (c,d) Tau, isovolumic relaxation constant. C, Control (n = 6); D, Diabetic (n = 7); SV, Sacubitril/valsartan-treated diabetic (n = 6); and V, Valsartan-treated diabetic (n = 7). ** p < 0.01; *** p < 0.001 compared to control.
