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. 2024 Sep 30;25(19):10529. doi: 10.3390/ijms251910529

Figure 1.

Figure 1

Home-cage voluntary ethanol consumption in a 2-bottle free choice test. (A,B) Weekly intermittent 20% ethanol intake in water and AO-treated cohorts, respectively. (C) Average ethanol intake over the last 4 weeks of the experiment. (D) Average preference ratio over the last week of the experiment of Ctrl (n = 12), IEI (n = 12), UMS (n = 12) and IEI/UMS (n = 12) with/without AO treatment. Results were expressed as mean ± SEM. (A,B): aaa p < 0.001, IEI vs. Ctrl; ccc p < 0.001, Ctrl vs. IEI/UMS. (C,D): aaa p < 0.001 compared with Ctrl; bbb p < 0.001 compared with IEI; ccc p < 0.001 compared with UMS, according to RM 3-way or 2-way ANOVA, followed by a Tukey’s test.