TABLE 2.
Differences in nucleotides and predicted amino acids of HBV polymerase between isolates 2-18 and 56
| P gene portion and amino acid position | 2-18
|
56
|
||
|---|---|---|---|---|
| Amino acid | Codon | Amino acid | Codona | |
| TP | ||||
| 74 | W | TGG | G | 2528GGG |
| 110 | T | ACT | I | A2637TT |
| 139 | N | AAT | D | 2723GAT |
| Spacer | ||||
| 219 | S | AGT | R | AG2965A |
| 246 | G | CAG | R | C3044GG |
| 261 | R | CGC | G | 3089GGC |
| 270 | S | AGC | N | A3117AC |
| 272 | S | TCC | A | 3122GCC |
| 300 | H | CAT | R | C3207GT |
| RT | ||||
| 617 | M | ATG | L | 942CTG |
| 652 | S | TCT | P | 1047CCT |
| 682 | V | TGT | L | T1137CT |
| RNase H | ||||
| 720 | V | TGT | L | T1251CT |
| 805 | L | TTG | F | TT1508C |
| 809 | S | TCC | T | 1518ACC |
a
The position of the altered nucleotide is indicated as a superscript to the left of the changed base.