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. 2024 Oct 15;11(Suppl 2):S146–S155. doi: 10.1093/ofid/ofae503

Table 5.

Animal Species at Risk of Monkeypox Virus Infection

Animal Groups
Wild Domestic Pets
Nonhuman primates Rodents Other
  • Sooty mangabey monkey (Cercocebus atys)

  • Rhesus macaques (Macaca mulatta)

  • Cynomolgus macaque (Macaca fascicularis)

  • Asian monkeys

  • Wild chimpanzees (Pan troglodytes)

  • Red-tailed monkey (Cercopithecus ascanius)

  • Allen's swamp monkey (Allenopithecus nigroviridis)

  • Lesser spot-nosed monkey (Cercopithecus petaurista)

  • Western red colobus (Piliocolobus badius)

  • Orangutans

  • Gorillas

  • Chimpanzees

  • Gibbons

  • Marmosets

  • Lesser and greater white-nosed-monkeys

  • Grivets

  • Red colobus monkeys

  • Bonobos

  • Common marmoset (Callithrix jacchus)

  • Asian orangutans (Pongo pygmaeus)

  • African gorillas (Gorilla gorilla)

  • Chimpanzees (Pan troglodytes)

  • Asian gibbon (Hylobates lar)

  • South American squirrel monkeys (Saimiri sciureus)

  • African owl-faced monkeys (Cercopithecus hamlyni)

  • South American common marmoset (Hapale jacchus)

  • Gambian pouched rat (Cricetomys gambianus)

  • Emin's pouched rat (Cricetomys emini)

  • Prairie dogs (Cynomys spp)

  • Sun squirrel (Heliosciuris spp)

  • Jerboas (Jaculus spp)

  • Woodchucks (Marmota monax)

  • Porcupines (Atherurus africanus)

  • Brushtail porcupines (Atherurus spp)

  • Rope squirrel (Funisciurus anerythrus)

  • Congo rope squirrel (Funisciurus congicus)

  • Tree squirrels (Heliosciurus spp)

  • Mice (Mus musculus)

  • Striped mice (Lemniscomys spp)

  • African dormice (Graphiurus spp)

  • Natal multimammate rats (Mastomys natalensis)

  • Gambian sun squirrel

  • Marmot

  • Groundhog

  • Chinchilla (Chinchilla sp)

  • Giant pouched rat

  • Hamsters (Cricetus spp)

  • African brush-tailed porcupines

  • Rope squirrels (Funisciurus spp)

  • Tree squirrels (Heliosciurus sp)

  • Gambian giant pouched rats (Cricetomys sp)

  • Brushtail porcupines (Atherurus sp)

  • Dormice (Graphiurus sp)

  • Striped mice (Hybomys sp)

  • Striped mice (Lemiscomys barbarous)

  • Brush-tailed porcupines (Atherurus africanus)

  • Black-tailed prairie dogs (Cynomys ludovicianus)

  • Jerboa (Jaculus sp)

  • Chinchillas (Chinchilla lanigera)

  • Rat (Rattus sp)

  • Dwarf hamster (Allocricetulus sp)

  • Gerbil (Gerbillus sp)

  • Mole rat (Heterocephalus sp)

  • Roof rat (Rattus rattus)

  • Southern opossum (Didelphis marsupialis)

  • African hedgehogs (Atelerix sp)

  • Short-tailed opossum (Monodelphis domestica)

  • Giant anteaters (Myrmecophaga tridactyla)

  • Elephant shrew (Petrodromus tetradactylus)

  • Wild pig (Sus scrofa)

  • Rabbits (Oryctolagus cuniculus)

  • Hedgehog (Atelerix sp)

  • Shrew

  • Anteaters

  • Opossums

  • Coatimundis (Nasua nasua)

The susceptibility of production animals (cattle, goats, sheep) is the least known.
However, as most ruminants are susceptible to other poxviruses (such as cowpox), this should not be overlooked
The susceptibility of pets (such as cats) is unknown. May act as accidental hosts and cause viral spillover.
Dogs and ferrets are also regarded in this instance.

The following species have been experimentally found to be susceptible to monkeypox virus infection: CAST/EiJ, PERA/EiJ, and MOLF/EiJ mice; cynomolgus monkeys; Kellen's dormouse (Graphiurus kelleni); black-tailed prairie dogs (Cynomys ludovicianus); Thomas's rope squirrel (Funisciurus anerythrus); ground squirrels (Ictidomys tridecemlineatus); Gambian pouched rats (Cricetomys gambianus); and albino rabbits; as well as neonates of rats and exotic pet mice.