Figure 5.
Within A2/C2 and AP, METH does not decrease catecholamine neurons. Immunohistochemical analysis for TH was performed in dissected brains of mice following repeated METH administration (5 mg/kg, i.p., for 5 days). Mice were sacrificed 60 min following the METH challenge, which was carried out on day 11. TH-positive cell density (n/mm2) counted in saline- and METH-treated mice is shown in (A,B), respectively. Values are the means ± S.E.M. Representative images or TH-positive neurons in A2/C2 and AP of mice treated with saline or METH are shown in (C).