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Repeated administrations of METH increase HSP70 within A1/C1 neurons. Representative images of the double immunostaining for TH and HSP70 in A1/C1 within the RVLM and CVLM of mice treated with saline or METH are shown in (A,B), respectively. The densitometry values (OD: Optical Density) of HSP70 immunoreactivity (ir) are shown in (A’,B’), respectively. Values are the means ± S.E.M. * p < 0.05 (two-tailed Mann–Whitney test).
