Figure 2.

Ligand-binding pose and the ligand interaction map for the PRX (A,B) and SK609 (C,D) in D3R. D3R is shown in the cartoon model with a blue and purple color, respectively, for the D3R-PRX and D3R-SK609 complexes, respectively. PRX and SK609 are shown in the stick models with a green color. Important residues are shown as the black lines and are labeled. The helices are also labeled TM2-7. Nitrogen, oxygen, and hydrogen are shown in blue, red, and white colors, respectively. The distances are shown in the yellow dashed lines and are measured in the Å unit.