Table 1.
Baseline patient characteristics.
| Macrotextured | Microtextured | Nanotextured | p * | |
|---|---|---|---|---|
| No. of breasts (Ref) (%) | 22 | 43 | 82 | |
| No. of patients (%) | 20 | 32 | 57 | |
| Diagnosis | 0.001 | |||
| DCIS: n (%) | 5 (23) | 15 (35) | 9 (11) | |
| IDC: n (%) | 17 (77) | 23 (54) | 49 (60) | |
| Risk-reducing: n (%) | 0 (0.0) | 5 (12) | 24 (29) | |
| Laterality | 0.25 | |||
| Unilateral: n (%) | 18 (82) | 21 (49) | 32 (39) | |
| Bilateral: n (%) | 4 (18) | 22 (51) | 50 (61) | |
| Median smoking [IQR], pack years | 0 [0.0, 3.1] | 0 [0.0, 20] | 0 [0.0, 10] | 0.37 |
| Mean BMI ± SD: (kg/m2) | 22 ± 4 | 23 ± 4 | 24 ± 4 | 0.14 |
| Mean age at mastectomy ± SD: (yr) | 50 ± 13 | 50 ± 9 | 52 ± 10 | 0.46 |
| Cardiovascular disease: n (%) | 2 (9.1) | 12 (28) | 22 (27) | 0.21 |
| COPD and asthma: n (%) | 2 (9.1) | 7 (16) | 7 (8.5) | 0.43 |
| Dermatologic conditions: n (%) | 3 (14) | 3 (7.0) | 2 (2.4) | 0.06 |
| Diabetes: n (%) | 0 (0.0) | 0 (0.0) | 3 (3.7) | 0.73 |
| Neoadjuvant chemotherapy: n (%) | 8 (36) | 13 (30) | 39 (48) | 0.16 |
| PMRT: n (%) | 5 (23) | 8 (19) | 21 (26) | 0.68 |
| Hormone therapy: n (%) | 16 (73) | 25 (58) | 45 (55) | 0.32 |
| ASA Score: n (%) | 0.26 | |||
| I | 2 (9.1) | 0 (0.0) | 4 (4.9) | |
| II | 20 (91) | 40 (93) | 75 (92) | |
| III | 0 (0.0) | 3 (7.0) | 3 (3.7) | |
| IV | 0 (0.0) | 0 (0.0) | 0 (0.0) | |
| Mean mastectomy weight ± SD: (g) | 320 ± 2 | 400 ± 2 | 400 ± 2 | 0.20 |
| Sentinel lymph node biopsy: n (%) | 18 (82) | 28 (65) | 46 (56) | 0.08 |
| Axillary lymph node dissection: n (%) | 10 (46) | 11 (26) | 19 (23) | 0.12 |
| Mastectomy type: n (%) | 0.11 | |||
| SSM | 6 (27) | 7 (16) | 14 (17) | |
| NSM | 14 (64) | 21 (49) | 37 (45) | |
| SRM | 1 (4.5) | 14 (33) | 28 (34) | |
| MS | 1 (4.5) | 1 (2.3) | 3 (3.7) | |
| Mean TE volume ± SD: (cc) | 430 ± 97 | 500 ± 115 | 510 ± 130 | 0.04 |
| TE placement: n (%) | <0.001 | |||
| Subpectoral | 13 (59) | 16 (37) | 4 (4.9) | |
| Prepectoral | 9 (41) | 27 (63) | 78 (95) | |
| Usage of synthetic mesh or ADM: n (%) | 0.001 | |||
| None | 14 (64) | 31 (72) | 69 (84) | |
| Synthetic mesh (VicrylTM) | 8 (36) | 10 (23) | 4 (4.9) | |
| ADM | 0 (0.0) | 2 (4.7) | 9 (11) | |
| Evaluation of capsular contracture ± SD (months) | 9.9 ± 6.0 | 7.2 ± 5.0 | 6.3 ± 4.0 | 0.003 |
DCIS, ductal carcinoma in situ, IDC, invasive ductal carcinoma; IQR, interquartile range; BMI, body mass index; COPD, chronic obstructive pulmonary disease, ASA, American Society of Anesthesiologists, PMRT, post-mastectomy radiation therapy; SSM, skin-sparing mastectomy; NSM, nipple-sparing mastectomy; SRM, skin-reducing mastectomy; MS, mastectomy simplex; TE, tissue expander, ADM, acellular dermal matrix. * p < 0.05 (bold).