Table 4.

PSA screening recommendations from major North American guiding bodies

	Canadian Preventive Task Force (2014)2	CUA (2017)44	USPSTF (2018)45	AUA (2023)46	NCCN (2024)28
Screening for general population	Against PSA screening for all ages	Through shared decision-making with a healthcare provider: Undergo PSA screening ≥50 years	Through shared decision-making with a healthcare provider: Undergo PSA screening between 55–69 years Against PSA screening >70 years	Through shared decision-making with a healthcare provider: Undergo PSA screening beginning at age 45–50 years	Through shared decision-making with a healthcare provider: Undergo PSA screening between age 45–75 years
Screening for increased risk population	N/A	Undergo PSA screening ≥45 years	N/A	Undergo PSA screening beginning at age 40–45 years	Undergo PSA screening between age 40–75 years

AUA: American Urological Association; CUA: Canadian Urological Association; NCCN: National Comprehensive Cancer Network; PSA: prostate-specific antigen; USPSTF: U.S. Preventive Services Task Force.