Table A1.
Variable | Comparison | Estimated Effect | Lower 95% CL | Upper 95% CL | p-Value |
---|---|---|---|---|---|
Univariable median regression analysis | |||||
Randomization group | Sevoflurane vs. Desflurane | 1.746 | −1.331 | 4.823 | 0.267 |
Age | 0.615 | 0.459 | 0.772 | <0.001 | |
BMI | 0.027 | −0.236 | 0.290 | 0.840 | |
Sex | Male vs. Female | 6.000 | 3.865 | 8.135 | <0.001 |
ASA | III vs. I–II | 5.000 | 2.502 | 7.498 | <0.001 |
Baseline troponin T | 0.941 | 0.858 | 1.025 | <0.001 | |
Duration of anesthesia | 0.012 | −0.012 | 0.036 | 0.329 | |
Type of surgery | |||||
Urologic vs. General | 6.094 | 1.447 | 10.742 | 0.011 | |
Gynecologic vs. General | 0.764 | −3.729 | 5.257 | 0.739 | |
Gynecologic vs. Urologic | −5.330 | −7.534 | −3.127 | <0.001 | |
Intraoperative MAP | 0.167 | 0.008 | 0.327 | 0.041 | |
Beta-blocker | Yes vs. No | 4.000 | 0.892 | 7.108 | 0.013 |
Ca2+ channel blocker | Yes vs. No | 2.556 | −0.516 | 5.628 | 0.105 |
Aspirin | Yes vs. No | 4.000 | 0.094 | 7.906 | 0.046 |
Statin | Yes vs. No | 4.000 | 0.557 | 7.443 | 0.024 |
Xa inhibitor | Yes vs. No | 4.000 | −1.045 | 9.045 | 0.122 |
ACE inhibitor | Yes vs. No | 5.000 | 2.564 | 7.436 | <0.001 |
Hypertension | Yes vs. No | 5.000 | 2.702 | 7.298 | <0.001 |
Myocardial infarction | Yes vs. No | 12.000 | 0.304 | 23.696 | 0.046 |
Diabetes II | Yes vs. No | 3.502 | 0.042 | 6.962 | 0.049 |
Multivariable median regression analysis | |||||
Age | 0.017 | −0.112 | 0.147 | 0.795 | |
Sex | Male vs. Female | 0.309 | −1.598 | 2.216 | 0.751 |
ASA | III vs. I–II | 1.323 | −0.107 | 2.752 | 0.072 |
Baseline troponin T | 0.895 | 0.762 | 1.028 | <0.001 | |
Type of surgery | |||||
Urologic vs. General | 0.130 | −1.845 | 2.104 | 0.898 | |
Gynecologic vs. General | −0.586 | −2.260 | 1.087 | 0.493 | |
Gynecologic vs. Urologic | −0.716 | −2.587 | 1.155 | 0.454 | |
Intraoperative MAP | 0.024 | −0.052 | 0.099 | 0.536 | |
Beta-blocker | Yes vs. No | 1.101 | −0.361 | 2.563 | 0.142 |
Aspirin | Yes vs. No | 0.073 | −1.785 | 1.931 | 0.938 |
Statin | Yes vs. No | −0.322 | −1.855 | 1.210 | 0.681 |
ACE inhibitor | Yes vs. No | −0.657 | −2.458 | 1.144 | 0.476 |
Hypertension | Yes vs. No | 0.273 | −1.567 | 2.113 | 0.772 |
Myocardial infarction | Yes vs. No | 0.629 | −2.743 | 4.001 | 0.715 |
Diabetes II | Yes vs. No | −0.308 | −2.000 | 1.384 | 0.722 |
CL, confidence limit; BMI, body mass index; ASA, American Society of Anesthesiologists physical status; MAP, mean arterial pressure; ACE, angiotensin converting enzyme.