Table A3.

Univariable and multivariable median regression models for postoperative maximum copeptin concentrations.

Variable	Comparison	Estimated Effect	Lower 95% CL	Upper 95% CL	p-Value
Univariable median regression analysis
Randomization group	Sevoflurane vs. Desflurane	−6.325	−16.579	3.929	0.228
Age		0.697	−0.137	1.531	0.103
BMI		−0.012	−0.771	0.747	0.976
Sex	Male vs. Female	3.052	−6.471	12.574	0.531
ASA	III vs. I–II	6.710	−3.293	16.713	0.190
Baseline copeptin		1.336	0.958	1.714	<0.001
Duration of anesthesia		0.148	0.046	0.250	0.005
Type of surgery
	Urologic vs. General	−10.598	−30.838	9.642	0.306
	Gynecologic vs. General	−12.455	−34.511	9.601	0.270
	Gynecologic vs. Urologic	−1.857	−10.479	6.766	0.673
Intraoperative MAP		0.131	−0.268	0.529	0.521
Beta-blocker	Yes vs. No	6.174	−5.330	17.678	0.294
Ca2+ channel blocker	Yes vs. No	−0.120	−12.316	12.077	0.985
Aspirin	Yes vs. No	3.700	−14.218	21.619	0.686
Statin	Yes vs. No	−2.353	−9.962	5.255	0.545
Xa inhibitor	Yes vs. No	2.891	−5.488	11.270	0.500
ACE inhibitor	Yes vs. No	−8.433	−19.299	2.432	0.130
Hypertension	Yes vs. No	−1.941	−12.881	8.999	0.728
Myocardial infarction	Yes vs. No	8.680	−4.898	22.258	0.212
Diabetes II	Yes vs. No	10.180	−1.263	21.623	0.083
Multivariable median regression analysis
Baseline copeptin		1.217	0.985	1.450	<0.001
Duration of anesthesia		0.130	0.037	0.223	0.007

CL, confidence limit; BMI, body mass index; ASA, American Society of Anesthesiologists physical status; MAP, mean arterial pressure; ACE, angiotensin converting enzyme.