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. 2024 Oct 6;13(19):5946. doi: 10.3390/jcm13195946

Table A3.

Univariable and multivariable median regression models for postoperative maximum copeptin concentrations.

Variable Comparison Estimated Effect Lower 95% CL Upper 95% CL p-Value
Univariable median regression analysis
   Randomization group Sevoflurane vs. Desflurane −6.325 −16.579 3.929 0.228
   Age 0.697 −0.137 1.531 0.103
   BMI −0.012 −0.771 0.747 0.976
   Sex Male vs. Female 3.052 −6.471 12.574 0.531
   ASA III vs. I–II 6.710 −3.293 16.713 0.190
   Baseline copeptin 1.336 0.958 1.714 <0.001
   Duration of anesthesia 0.148 0.046 0.250 0.005
   Type of surgery
Urologic vs. General −10.598 −30.838 9.642 0.306
Gynecologic vs. General −12.455 −34.511 9.601 0.270
Gynecologic vs. Urologic −1.857 −10.479 6.766 0.673
   Intraoperative MAP 0.131 −0.268 0.529 0.521
   Beta-blocker Yes vs. No 6.174 −5.330 17.678 0.294
   Ca2+ channel blocker Yes vs. No −0.120 −12.316 12.077 0.985
   Aspirin Yes vs. No 3.700 −14.218 21.619 0.686
   Statin Yes vs. No −2.353 −9.962 5.255 0.545
   Xa inhibitor Yes vs. No 2.891 −5.488 11.270 0.500
   ACE inhibitor Yes vs. No −8.433 −19.299 2.432 0.130
   Hypertension Yes vs. No −1.941 −12.881 8.999 0.728
   Myocardial infarction Yes vs. No 8.680 −4.898 22.258 0.212
   Diabetes II Yes vs. No 10.180 −1.263 21.623 0.083
Multivariable median regression analysis
   Baseline copeptin 1.217 0.985 1.450 <0.001
   Duration of anesthesia 0.130 0.037 0.223 0.007

CL, confidence limit; BMI, body mass index; ASA, American Society of Anesthesiologists physical status; MAP, mean arterial pressure; ACE, angiotensin converting enzyme.