Skip to main content
. 2024 Oct 7;29(19):4737. doi: 10.3390/molecules29194737

Figure 4.

Figure 4

Schematic images of the secondary structure of (A) the hammerhead ribozyme–substrate complex and (B) the 10–23 DNAzyme–substrate complex. The red arrow indicates the cleavage site of the substrate RNA. (A) The hammerhead ribozyme consists of an intrastrand helix (helix II) and two interstrand helixes (helix I and III) generated after hybridizing with substrate RNA and a conserved unpaired catalytic core. (B) The 10–23 DNAzyme consists of two variable binding arms, I and II, on both sides of the conserved (15 nt) and unpaired catalytic core. R represents A or G; Y represents U (or T) or C; H represents A, C, or U; N represents A, U (or T), C, or G.