Table 3.
Acute toxicity during induction chemotherapy
| Toxicity | GP group (n=41) | TPF group (n=40) | P value |
|---|---|---|---|
| No (%) | No (%) | ||
| Anemia | |||
| G1-2 | 38 (92.7) | 34 (85) | 0.271 |
| ≥G3 | 3 (7.3) | 6 (15) | |
| Leucopenia | |||
| G1-2 | 36 (87.8) | 28 (70) | 0.040 |
| ≥G3 | 5 (12.2) | 12 (30) | |
| Febrile neutropenia | |||
| No | 39 (95.1) | 32 (80) | 0.039 |
| Yes | 2 (4.9) | 8 (20) | |
| Thrombocytopenia | |||
| G1-2 | 38 (92.7) | 40 (100) | 0.081 |
| ≥G3 | 3 (7.3) | 0 (0.0) | |
| Nausea/vomiting | |||
| G1-2 | 37 (90.2) | 33 (82.5) | 0.309 |
| ≥G3 | 4 (9.8) | 7 (17.5) | |
| Mucositis | |||
| G1-2 | 40 (97.6) | 34 (85) | 0.044 |
| ≥G3 | 1 (2.4) | 6 (15) | |
| Diarrhea | |||
| G1-2 | 40 (97.6) | 36 (90) | 0.157 |
| ≥G3 | 1 (2.4) | 4 (10) |