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Correlation between AS and copy-number signatures
| Signature | Spearman’s r | P value | Putative cause according to Drews et al. [10] |
|---|---|---|---|
| CX4 | 0.254 | < 0.001 | PI3K-AKT-mediated toleration of whole-genome duplication |
| CX6 | 0.420 | < 0.001 | Chromosome missegregation via defective mitosis |
| CX8 | 0.348 | < 0.001 | Replication stress |
| CX11 | -0.168 | 0.012 | Replication stress |
| CX12 | -0.153 | 0.023 | Unknown |
