Table 2.

List of FDA-approved TKIs

Targeted kinase	Name of the drugs
ALK	Alectinib, Crizotinib, Brigatinib, Lorlatinib, Ceritinib
Bcr-Abl	Bosutinib, Dasatinib, Nilotinib, Ponatinib, Imatinib
BTK	Acalabrutinib, Ibrutinib, Zarubrutinib
C-Met	Crizotinib, Cabozantinib
EGFR	Erlotinib, Afatinib, Gefitinib, Dacomitinib, Osimertinib, Neratinib
JAKs	Ruxolitinib, Baricitinib, Tofacitinib
PDGFR	Lenvatinib, Nintedanib, Ponatinib, Regorafenib, Imatinib
RET	Lenvatinib, Regorafenib, Sunitinib, Vandetanib
SRC	Dasatinib, Bosutinib, Ponatinib
VEGFR	Axitinib, Lenvatinib, Regorafenib, Pazopanib, Nintedanib, Sorafenib, Sunitinib
FGFR	Nintedanib, Erdafitinib
c-Kit	Pexidartinib, Avapritinib
FLT3	Gelteritinib, Sunitinib